Immunogenomics of Disease: Accelerating to Patient Miscellaneous

This new conference aims to bring together scientists working in the fields of molecular immunology, functional genomics and immune-mediated

Next generation sequencing has accelerated the discovery of highly penetrant causal variants in diverse primary immune deficiencies, providing insight into the non-redundant functions of the affected genes and pathways in human immunity. In parallel, the application of GWAS has been arguably most successful in immune-related traits, such that together we now have evidence of the role of genetic variation in susceptibility to various immune diseases across the prevalence spectrum. To accelerate the translation of these discoveries into the clinic, we urgently need to improve our understanding of the molecular consequences of disease-associated variants, immunological processes and drug target discovery.

This meeting will focus on recent successful stories in immune-mediated disease gene-mapping, causal variant identification in common and rare immune diseases, and efforts to understand the cellular consequences of these variants on the innate and adaptive immune system. We will highlight technological developments that promise to deliver further insight into the biology of the immune system in both health and disease, such as single cell sequencing, metagenomic sequencing and genome editing.

Topics will include:
- Autoimmunity and autoinflammation
- Primary immune deficiencies
- Immunology and the microbiome
- Genomic diversity of immune cells
- Immune regulation and homeostasis

Price:
Student registration from TBC: GBP 281
Academic registration from TBC: GBP 381
Commercial registration from TBC: GBP 481

Category: Conferences | Science, Health & Medicine | Genetic Medicine | Human Genetics

Speakers: John Todd (University of Cambridge, UK), Mike Lenardo (National Institutes of Health, USA), Ivona Aksentijevich (National Institutes of Health, USA), Mary Carrington (National Cancer Institute Center for Cancer Research, USA), Yanick Crow (Imagine Institute, France), Lars Fugger (University of Oxford, UK) Michel Georges (University of Liege, Belgium), Claire Harris (Cardiff University, UK), Eric Meffre (Yale University, USA), Anjana Rao (La Jolla Institute for Allergy & Immunology, USA), Soumya Raychaudhuri (Harvard Medical School, USA), Sarah Teichmann (Wellcome Trust Sanger Institute, UK), Gosia Trynka (Wellcome Trust Sanger Institute, UK), Holm Uhlig (University of Oxford, UK), Cisca Wijmenga (University of Groningen, The Netherlands)

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